Joseph H Neale Selected Research

metabotropic glutamate receptor 3 (mGluR3)

9/2017	NAAG Peptidase Inhibitors Act via mGluR3: Animal Models of Memory, Alzheimer's, and Ethanol Intoxication.
9/2012	NAAG peptidase inhibition in the periaqueductal gray and rostral ventromedial medulla reduces flinching in the formalin model of inflammation.
4/2012	mGluR3 and not mGluR2 receptors mediate the efficacy of NAAG peptidase inhibitor in validated model of schizophrenia.
2/2011	Type 2 metabotropic glutamate receptor (mGluR2) fails to negatively couple to cGMP in stably transfected cells.
9/2010	Endogenous N-acetylaspartylglutamate (NAAG) inhibits synaptic plasticity/transmission in the amygdala in a mouse inflammatory pain model.

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Joseph H Neale Research Topics

Disease

9	Pain (Aches) 01/2017 - 03/2004
7	Schizophrenia (Dementia Praecox) 06/2012 - 05/2004
6	Traumatic Brain Injuries (Traumatic Brain Injury) 04/2016 - 02/2005
5	Neuralgia (Stump Neuralgia) 09/2012 - 07/2004
4	Inflammation (Inflammations) 01/2017 - 01/2007
2	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 09/2017
2	Memory Disorders (Memory Loss) 09/2017 - 02/2013
2	Bone Neoplasms (Bone Cancer) 01/2017 - 09/2006
2	Stroke (Strokes) 08/2011 - 09/2005
2	Hyperalgesia 09/2010 - 07/2004
1	Prostatic Neoplasms (Prostate Cancer) 01/2020
1	Nervous System Diseases (Neurological Disorders) 02/2013
1	Psychotic Disorders (Schizoaffective Disorder) 06/2012
1	Cocaine-Related Disorders (Cocaine Addiction) 08/2011
1	Peripheral Nervous System Diseases (PNS Diseases) 08/2011
1	Glioma (Gliomas) 02/2011
1	Brain Injuries (Brain Injury) 05/2006
1	Neoplasms (Cancer) 12/2005
1	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 09/2005
1	Nervous System Trauma 09/2005
1	Diabetic Neuropathies (Diabetic Neuropathy) 09/2005
1	Carcinoma (Carcinomatosis) 05/2004
1	Epilepsy (Aura) 01/2003
1	Hypoxia (Hypoxemia) 09/2002

Drug/Important Bio-Agent (IBA)

15	Glutamate Carboxypeptidase II (N-Acetylaspartylglutamate Peptidase)IBA 09/2017 - 05/2004
8	Glutamic Acid (Glutamate)FDA Link 01/2017 - 02/2005
8	isospaglumic acid (NAAGA)IBA 09/2012 - 07/2004
6	EnzymesIBA 01/2017 - 05/2004
6	Formaldehyde (Formol)FDA Link 01/2017 - 07/2004
5	metabotropic glutamate receptor 3 (mGluR3)IBA 09/2017 - 09/2010
5	Analgesics (Analgesic Drugs)IBA 01/2017 - 07/2004
5	Phencyclidine (Angel Dust)IBA 06/2012 - 05/2004
4	metabotropic glutamate receptor 2IBA 09/2017 - 09/2010
4	ZJ43IBA 09/2017 - 01/2008
4	Peptides (Polypeptides)IBA 04/2016 - 01/2007
3	N-Methylaspartate (NMDA)IBA 06/2012 - 09/2006
3	Metabotropic Glutamate Receptors (Metabotropic Glutamate Receptor)IBA 07/2011 - 09/2002
2	Neurotransmitter Agents (Neurotransmitter)IBA 09/2010 - 09/2005
2	Peptide Hydrolases (Proteases)FDA Link 09/2010 - 12/2005
2	Dizocilpine Maleate (Dizocilpine)IBA 01/2008 - 09/2006
2	Morphine (MS Contin)FDA LinkGeneric 09/2006 - 03/2004
1	Ethanol (Ethyl Alcohol)IBA 01/2020
1	Proteins (Proteins, Gene)FDA Link 01/2020
1	Norepinephrine (Noradrenaline)FDA LinkGeneric 01/2017
1	Adrenergic Receptors (Adrenergic Receptor)IBA 01/2017
1	Dopamine (Intropin)FDA LinkGeneric 06/2012
1	Glutamate Receptors (Glutamate Receptor)IBA 06/2012
1	eglumetadIBA 07/2011
1	Excitatory Amino Acid AgonistsIBA 07/2011
1	Dextroamphetamine (Dexedrine)FDA LinkGeneric 07/2011
1	Complementary DNA (cDNA)IBA 02/2011
1	N-Methyl-D-Aspartate Receptors (NMDA Receptors)IBA 01/2008
1	CarrageenanIBA 01/2007
1	Clonidine (ST 155)FDA LinkGeneric 09/2006
1	Dexmedetomidine FDA Link 09/2006
1	Ketamine FDA LinkGeneric 09/2006
1	glutamate carboxypeptidaseIBA 05/2004
1	Urea (Carbamide)FDA LinkGeneric 03/2004
1	GABA-A Receptors (GABA(A) Receptor)IBA 01/2003

Therapy/Procedure

4	Analgesia 09/2012 - 03/2004
3	Therapeutics 01/2020 - 12/2005
2	Spinal Injections 01/2017 - 07/2004
1	Ligation 07/2004
1	Intravenous Administration 07/2004
1	Pain Management 03/2004